Parkinson's disease is a progressive, neurodegenerative disorder of the melanin-containing-dopaminergic neurons in the anterior part of the substantia nigra pars compacta. Pars compacta are involved in tonal modulation. In this video, Dr. Mobeen Syed discusses the types of Parkinson's disease, which are idiopathic, hereditary, acquired, and Parkinson's plus.
Most people with parkinsonism have idiopathic-Parkinson's disease. Idiopathic means the cause is unknown.
Hereditary Parkinson's disease can be autosomal-dominant or autosomal-recessive. Parkinson's disease can run in families as a result of faulty genes being passed to a child by their parents, but it is rare.
In Parkinson's plus, there are other diseases associated with Parkinson's disease.
Dr. Mobeen Syed also describes the prevalence and prognosis of Parkinson's disease.
The prevalence increases with the increase of age. The prevalence increases by 3% after 60-80 years of age.
The condition usually worsens over an average of 15 years. The rate of progression and its course varies among patients. The course is relatively benign in patients with little disability after twenty years, and maybe more aggressive among others who may be severely disabled after ten years.
The causes of death in patients with Parkinson's disease are infections and postural instability.
The following topics have discussed in the full video:
* Definition of Parkinson's disease
* Types of Parkinson's disease
* Prevalence of Parkinson's disease
* Prognosis of Parkinson's disease
* Dopaminergic pathways
* Morphology of Parkinson's disease
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